Physical Organic Chemistry (Research)
The School of Chemistry has developed a particular strength in Physical Organic Chemistry, with a research group dedicated to this exciting area of study. As part of the Chemistry (PhD/MPhil) program, students can conduct their research within this group.
The Physical Organic Chemistry Centre is housed in state-of-the-art laboratories (built in 2007) within the School of Chemistry. The topics being investigated are extremely wide ranging, stretching from the development of new methods for catalysing reactions, through the development of better understanding of organic reactions in aqueous solutions, to the development of biosensors and the directed assembly of functional multicomponent systems. Underpinning this breadth of applications is the detailed, quantitative understanding of the fundamental properties and reactions and interactions of organic molecules.
The techniques used in the research are as widely varying as the topics being studied. Theoretical methods include electronic structure theory, molecular dynamics simulations, integration of complex kinetic equations, and development of data analysis software. In the laboratory, the research may involve organic synthesis, biophysical studies (including for example titration calorimetry, UV-visible, circular dichroism, infrared and NMR spectroscopy) and HPLC. MPhil and PhD students involved in this work can expect to receive a broad and interdisciplinary training that is highly marketable in a wide variety of chemistry-related careers.
Available research specialisations within this area:
- Fundamental studies of kinetics and dynamics of organic reactions.
- Design and synthesis of sequence-specific DNA biosensors.
- Study of reaction mechanisms of homogeneous catalysts
- Directed assembly of functional multicomponent nanostructures
- Racemisation of drug-like chiral centres
- Mechanistic studies of nanoparticle catalysis
The modules shown are an example of the typical curriculum and will be reviewed prior to the academic year. The final modules will be published by September.
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- Synthesis of novel organic and/or biological molecules.
- Physical and biophysical analysis methods
- Wide range of quantitative measurements and data analysis techniques.
- Computational techniques, including molecular mechanics, quantum chemistry and molecular dynamics simulations.
Training in physical organic chemistry equips students with skills that cross traditional boundaries, and consequently make them highly employable. Past students working with the staff have gone on to jobs in academia, in pharmaceutical companies, chemical companies, electronics companies, and teaching among many others.
About this institute
Founded in 1883, Cardiff University combines a prestigious heritage with impressive modern facilities, on one of the most beautiful campuses in the UK. As part of the Russell Group, our students benefit from our outstanding research quality and reputation, while...
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