Universidad Rey Juan Carlos

Máster de Formación Continuada en Patología Renal

Duration and Development

• Months: The degree lasts for 1 academic year.
• Hours: 600 teaching hours per academic year (Total number of credits: 60 ECTS)

Topics

Module 1

1. Histology of the normal kidney
2. Processing of renal samples. Techniques of study MO, in the IF,
3. immunohistochemistry and electron microscopy. Utility of its use.
4. Approach to the interpretation of renal biopsy. Part I and Part 2
5. Mechanisms of glomerular damage
6. Glomerular lesions and histologic patterns
7. Closed clinical cases
8. Evaluation

Module 2

1. Clinical Aspects of Hematuria and Proteinuria. Definition of nephrotic syndrome and nephritic syndrome.
2. Minimal change disease and focal and segmental Gn in the child.
3. Minimal change disease and Focal and segmental Gn in the adult
4. Membranous Gn
5. Other basement membrane diseases: Alport disease and thin basement membrane. Thin basement membrane.
6. Closed clinical cases
7. Evaluation

Module 3

1. Gn IgA. Oxford/MEST classification. IgA-associated vasculitis/ Schonlein-Henoch purpura.
2. Membranoproliferative Gn.
3. Gn associated with hepatitis C
4. Post-infectious Gn / persistent infections (endocarditis, shunt nephritis, etc.)
5. Lupus nephritis. ISN/RPS classification
6. Closed Clinical Cases
7. Evaluation

Module 4

1. Gn extracapillary pauci-inmnes. ANCAS vasculitis
2. Gn due to anti-glomerular basement membrane antibodies.
3. Closed clinical cases
4. Evaluation

Module 5

1. General pathophysiology of complement.
2. Thrombotic microangiopathies.
3. Hemolytic uremic syndrome. Syndrome
4. antiphospholipid syndrome, scleroderma, malignant hypertension.
5. Other forms of microangiopathy
6. Glomerulopathies C3.
7. Closed clinical cases
8. Evaluation

Module 6

1. Myeloma kidney. Monodonal gammopathies with significance.
2. Amyloidosis (Primary and secondary).
3. Glomerulopathies with organ deposits: fibrillary GN and GN.
4. Fabry disease. - Matrix deposition glomerulopathies.
5. Onconephrology
6. Closed clinical cases
7. Evaluation

Module 7

1. Diabetic nephropathy
2. Obesity nephropathy.
3. Nephroangiosclerosis/Ischemic Nephropathy.
4. Atheroembolic disease.
5. Closed clinical cases.
6. Evaluation

Module 8

1. Acute Tubular Necrosis.
2. Acute Interstitial Nephritis.
3. Chronic Interstitial Nephritis.
4. Nephropathy due to crystals: a. Calcium Oxalate Phosphate b - b. Calcium Phosphate - c. Calcium Phosphate
5. calcium phosphate - c. Drugs
6. Closed clinical cases
7. Evaluation

Module 9

1. Assessment of pre-transplant renal biopsy: Banff criteria and limitations of intraoperative
2. limitations of intraoperative biopsy
3. Graft rejection:

• Banff classification and basic transplant lesions (glomerulitis, peritubular capillaritis, tubulitis, vasculitis, interstitial fibrosis, tubular /tubular atrophy
• Humoral rejection (hyperacute, acute accelerated, and chronic)
• Cellular rejection (acute and chronic active),
  • Banff classification and basic transplant lesions (glomerulitis, peritubular capillaritis, tubulitis, vasculitis, interstitial fibrosis, tubular /tubular atrophy
  • Humoral rejection (hyperacute, acute accelerated, and chronic)
  • Cellular rejection (acute and chronic active),

1. Chronic graft glomerulopathy.
2. Nephrotoxicity due to immunosuppressive drugs.
3. Viral nephropathy: BK virus and CMV nephropathy.
4. Clinical cases
5. Evaluation