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Charles University Faculty of Pharmacy PhD in Bioorganic Chemistry
Charles University Faculty of Pharmacy

PhD in Bioorganic Chemistry

Hradec Kralove, Czech Republic

4 Years

English

Full time

Request application deadline *

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CZK 2,000 / per year **

Blended, On-Campus

* applicants from non-EU/EEA countries are advised to apply by April 30th

** online application fee: 720 CZK. Paper application fee: 770 CZK

Key Summary

    About: The PhD in Bioorganic Chemistry focuses on the intersection of chemistry and biology, exploring the chemical processes that underpin biological systems. This program emphasizes hands-on laboratory work and theoretical study, enabling students to conduct research that can contribute to advancements in medicine, environmental science, and biotechnology.
    Career Outcomes: Graduates can pursue careers in academia, research institutes, pharmaceutical companies, or biotechnology firms. Potential roles include research scientist, laboratory manager, or academic lecturer. The skills learned can also lead to opportunities in regulatory affairs or consultancy.

Introduction

Postgraduate study in Bioorganic Chemistry serves for the education of chemical experts with an emphasis on the structure and functions of small organic molecules in living organisms and on the possibility of influencing biological processes in these organisms through the action of such molecules. The program is thus directed towards the study of all aspects of organic compounds, which are indispensable for the structure and functioning of living organisms. The broad spectrum of these compounds includes molecules with a building (primary metabolites) function, signaling function, activating or deactivating function in relationship to strategic proteins within the living organisms, and also compounds, which are produced by these organisms (natural products, secondary metabolites, metabolites of xenobiotics). The study is founded on the structure and synthesis of organic compounds with a focus on natural products, heterocycles, and other organic compounds, which are capable of modulating biological processes.

Elucidation of the function of such compounds as parts of biological structures as well as that of their influence on biological processes and the possibility to modify this influence through structural changes are no less important. Bioorganic Chemistry thus serves as a link between Organic Chemistry and biomedical disciplines and partially overlaps with Pharmaceutical and Medicinal Chemistry. Bioorganic Chemistry is, however, more general than the latter two programs, which are primarily focused on the study and development of drugs, ie. a more limited subgroup of biologically active compounds.

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